Methanone, (4-chloro-2-fluoro-5-methoxyphenyl)(1,3-dimethyl-1H-pyrazol-5-yl)- - Names and Identifiers
Name | 1H-Pyrazole-1,4-dicarboxylic acid, 2,3-dihydro-3-oxo-,1-(1,1-dimethylethyl) 4-ethyl ester
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Synonyms | Ethyl 3-hydroxy-1-Boc-pyrazole-4-carboxylate 1-tert-butyl 4-ethyl 3-hydroxy-1H-pyrazole-1,4-dicarboxylate 1-tert-butyl-4-ethyl-3-hydroxy-1H-pyrazole-1,4-dicarboxylate 1H-Pyrazole-1,4-dicarboxylic acid, 2,3-dihydro-3-oxo-,1-(1,1... 1-(tert-Butyl) 4-ethyl 3-oxo-2,3-dihydro-1H-pyrazole-1,4-dicarboxylate Methanone, (4-chloro-2-fluoro-5-methoxyphenyl)(1,3-dimethyl-1H-pyrazol-5-yl)- 1H-Pyrazole-1,4-dicarboxylic acid, 2,3-dihydro-3-oxo-,1-(1,1-dimethylethyl) 4-ethyl ester 1H-Pyrazole-1,4-dicarboxylic acid, 2,3-dihydro-3-oxo-, 1-(1,1-diMethylethyl) 4-ethyl ester
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CAS | 178424-17-4
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Methanone, (4-chloro-2-fluoro-5-methoxyphenyl)(1,3-dimethyl-1H-pyrazol-5-yl)- - Physico-chemical Properties
Molecular Formula | C11H16N2O5
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Molar Mass | 256.26 |
Storage Condition | 2-8°C |
Methanone, (4-chloro-2-fluoro-5-methoxyphenyl)(1,3-dimethyl-1H-pyrazol-5-yl)- - Introduction
1H-Pyrazole-1,4-dicarboxylic acid, 2,3-dihydro-3-oxo-,1-(1,1-dimethylethyyl) 4-ethyl ester is a commonly used organic synthesis intermediate with various properties and applications.
Nature:
1H-Pyrazole-1,4-dicarboxylic acid, 2,3-dihydro-3-oxo-,1-(1,1-dimenthylethyl) 4-ethyl ester is a solid with a white or off-white appearance. It is stable at room temperature and insoluble in water, but soluble in organic solvents such as ethanol, diethyl ether and dimethylformamide. It is a relatively stable compound and is not easily decomposed under regular experimental conditions.
Use:
In organic synthesis, 1H-Pyrazole-1,4-dicarboxylic acid, 2,3-dihydro-3-oxo-,1-(1,1-dimethylethyl) 4-ethyl ester is an important protecting agent. It can be used to protect the hydroxyl functional groups to prevent side reactions or irreversible changes in the reaction, so as to achieve the synthesis of target compounds. At the same time, it can also be used for the synthesis of polypeptides, Acyl Coenzyme A and other organic compounds.
Method:
The preparation of 1H-Pyrazole-1,4-dicarboxylic acid, 2,3-dihydro-3-oxo-,1-(1,1-dimethylethyyl) 4-ethyl ester is usually carried out by organic synthesis method. A common synthetic route is by reacting an activated hydroxylating reagent with 3-hydroxypyrazole-4-carboxylic acid methyl ester, followed by the introduction of a protecting group. The synthesis process needs to pay attention to the operating conditions and the purity of the reactants to ensure the purity and yield of the product.
Safety Information:
1H-Pyrazole-1,4-dicarboxylic acid, 2,3-dihydro-3-oxo-,1-(1,1-dimethylethyl) 4-ethyl ester is irritating and direct contact with skin and eyes should be avoided. Wear suitable protective gloves, glasses and lab coat during operation. It should be stored in a cool, dry, well-ventilated place, away from fire and oxidants. In case of accidental inhalation or ingestion, seek medical advice immediately.
Last Update:2024-04-09 21:11:58